Preparation and reactions of nitrilium triflates

  • 1.80 MB
  • 8709 Downloads
  • English
by
UMIST , Manchester
StatementSupervised by: Booth, B.L..
ContributionsBooth, B. L., Supervisor., Chemistry.
ID Numbers
Open LibraryOL21846596M

Pyridine N-oxides are highly versatile ambivalent species capable of reacting with both nucleophilic and electrophilic substitution at C-2, pyridine N-oxides provide a highly effective alternative to typical S N Ar chemistry 〈 CC, TL 〉.

An activating agent can simultaneously facilitate nucleophilic addition while serving to deoxygenate the pyridine ring. Metal triflates have been shown to activate this nitrilium intermediate making them more susceptible to nucleophilic attack by carboxylic acids and thereby increasing rates of U4CR product.

A simple and efficient methodology is presented for the synthesis of a wide range of substituted imines. It is based on stabilizing readily available, but thermally labile, N-alkylnitrilium triflates with pyridine or DMAP to moderately air-stable adducts.

These base-stabilized imine synthons react conveniently with phosphorus- and nitrogen-based nucleophiles to amidines and by: An efficient synthesis has been developed for the preparation of 9H-pyrrolo[1,2-a]indolones (fluorazones) from readily available anthranilic acid derivatives via a one-pot amide- and pyrrole-formation step, followed by an intramolecular cyclodehydration.

The cyclodehydration process is mediated by the activation of aromatic tertiary amides by triflic anhydride (Tf2O).Cited by: 4. Multicomponent reactions (MCRs) are extremely popular owing to their facile execution, high atom-efficiency and the high diversity of products.

Download Preparation and reactions of nitrilium triflates EPUB

MCRs can be used to access various heterocycles and highly functionalized scaffolds, and thus have been invaluable tools in total synthesis, drug discovery and bioconjugation. Traditional isocyanide-based MCRs utilize an external nucleophile attacking Cited by: K. Jibodu has written: 'Preparation and reactions of nitrilium triflates' Asked in Authors, Poets, and Playwrights What has the author K O Samuel written.

The preparation and reactions of the epimeric nor-5α-cholestanols are discussed, and substitution reactions of 5α-cholestanols are examined in regard to the steric effects of the 10β-methyl group on S N 2 mechanisms. Functionalization at specific unactivated positions in the nucleus has hitherto been carried out only by Barton-type.

A new method for the preparation of 2-aminocyanoquinolines from readily available aryldiazonium salts, 2-aminoarylketones and malononitrile via a cascade reaction is reported.

Allen, Phosphines and related C–P bonded compounds, in Organophosphorus Chemistry: Volpp. DOI: / eISBN: From Book Series: SPR - Organophosphorus ChemistryCited by: 4. Mechanistic Pathways in Amide Activation: Flexible Synthesis of Oxazoles and ImidazolesCited by: Reactions - Lesson 2 - Aromatic Substitution, Electrophilic - Introduction - This book explains the theories Preparation and reactions of nitrilium triflates book examples of organic chemistry, providing the most comprehensive resource about organic chemistry available.

Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. Reactions of the very toxic agent VX (; R CH2 CH2 NPri2) and the mildly toxic (; R Et) with HO2, HO, RO, and an oximate ion are seen as SN 2 P concerted reactions rather than stepwise with the formation of trigonal bipyramidal intermediates The ester exchange reactions of the oxyphosphoranes (; R R Ph, Me, 4nitrophenyl) with.

Named Organic Reactions, Second Edition T. Laue and A. Plagens John Wiley & Sons, Ltd ISBNs: (HB); X (PB) 1 82 Darzens Glycidic Ester Condensation.

Reactions - Aliphatic Substitution, Nucleophilic and Organometallic - Introduction - This book explains the theories and examples of organic chemistry, providing the most comprehensive resource about organic chemistry available.

Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The 7th edition proves again it is a.

Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes.

A fast and green method is developed for regioselective acylation of indoles in the 3-position without the need for protection of the NH position. The method is based on Friedel-Crafts acylation using acid anhydrides.

The method has been optimized, and Y(OTf)3 in catalytic amounts is found to be the best catalyst together with the commercially available ionic liquid [BMI]BF4 (1-butyl-3 Cited by: 8. These reactions proceed via the intermediacy of nitrilium adducts and feature N-oxide-promoted umpolung of the α-position of amides as well as a mechanistically intriguing sequence that results in sulfonyl migration from nitrogen to carbon.

Quantum-chem. mechanistic anal. sheds light on the intricacies of the : Daniel Kaiser, Christopher J. Teskey, Pauline Adler, Nuno Maulide.

The book provides a cornerstone for understanding basic reactions in chemistry and by extension the chemical basis for structure, function and change in the whole of science. It is a gateway to the future of the field and all fields dependent on a molecular view for innovative advancement. Organophosphorus chemistry is a very broad and exciting field, with potential opportunities to the researchers involved in multi-disciplinary areas of scientific endeavour including organic, medicinal, pharmaceutical, agricultural and industrial chemistry.

Full text of "Organic Synthesis with Carbohydrates" See other formats. Library of Congress Cataloging-in-Publication Data is available. Smith, Michael B., March, Jerry March’s Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, Sixth Edition ISBN ISBN Printed in the United States of America 10 9 8 7 6 5 4 3 2 1 CONTENTS PREFACE BIOGRAPHICAL NOTE ABBREVIATIONS.

Full text of "Name ReactionsAnd Reagents In Organic Synthesis" See other formats. Reactions at Carboxylic Acid Derivatives and Analogues Reactions of Carbonic Acid Derivatives reviews and highlight articles on iron catalysis have been published,2 9 the most comprehensive one being Plietker’s book Iron Catalysis in Organic Chemistry published in In addition, a large number of reviews, accounts.

Kulkarni et al. developed an efficient method for the preparation of 3-methylquinolinecarbaldehydes by reductive cyclization of nitroaldehydes a Nitroaldehydes was obtained from 2-nitro benzaldehyde after a series of reactions such as Wittig-olefination–Claisen-rearrangement etc.

Description Preparation and reactions of nitrilium triflates EPUB

similarly in Ramesh et al. used iron/acetic Cited by:   Rhodium (Chief Bee) No Archive of "Wanted References" Volume 1 The thread Post (Rhodium: "Wanted references", Novel Discourse) in this forum for requesting journal articles which are out of reach for yourself often becomes cluttered with posts after a while (so that it is hard to see which articles are still wanted and which has been retrieved), and as it is a waste.

Rhodium (Chief Bee) No Archive of "Wanted References" Volume 1 Bookmark: The thread Post (Rhodium: "Wanted references", Novel Discourse) in this forum for requesting journal articles which are out of reach for yourself often becomes cluttered with posts after a while (so that it is hard to see which articles are still wanted and which has been retrieved), and as.

New procedures for the preparation of this class of compounds include, e.g., rearrangement of u,-aziridino-c-amino esters. Synthesis of benzyl chloride by solid-liquid phase-transfer catalysis method Bui Thi Van Nga; Chu Pham Ngoc Son, Tap Chi Hoa Hoc 23(4), () Abstract PhCH 2 Cl was prepd.

by chlorination of PhMe with Ca(OCl) 2 using tetrabutylammonium hydrogen sulfate or tetrabutylammonium bromide as phase-transfer catalysts. With suitable ratio of PhMe-catalyst, the yield was high and the. Find link is a tool written by Edward Betts.

searching for Halide found ( total) alternate case: halide Haloalkane (2, words) exact match in snippet view article find links to article The haloalkanes (also known as halogenoalkanes or alkyl halides) are a group of chemical compounds derived from alkanes containing one or more halogens.

Details Preparation and reactions of nitrilium triflates FB2

Two possible reactions (isomerization and dehydrogenation) are presented. These reactions are found to be exothermic, with the best thermochemical conditions observed for the dehydrogenation reaction at around (-1).

Benjamín Aguilera-Venegas, Hernán Speisky, Identification of the transition state for fast reactions: The trapping of hydroxyl and methyl radicals by DMPO–A DFT approach, J. Mol. Graph. Model.Orga ic N~ons ~--Organic Name Reactions "This page is Intentionally Left Blank" Organic Name Reactions K.R.

Desai Oxford Book Company Jaipur India I ISBN: First Published Oxford Book Company.Organic Mechanisms Reactions, Stereochemistry and Synthesis Edited by Michael Harmata With a foreword by Paul A.

Wender Prof. Dr. Reinhard Bruckner Albert-Ludwigs-Universität Freiburg Institut für Organische Chemie und Biochemie Albertstr. 21 Freiburg [email protected].